Abstract: Background: It is estimated that about 80,000 children develop the disease each year. Objectives: To determine the effectiveness of health education program of diabetic children &their families. Methodology: The present study included 50 children with type1diabetes and their families, their age ranged from 6 to 10years; attended to National Institute of Diabetes & Endocrinology from 1st of July 2015 to the end of June 2016, for 6 months health educational program. Health education program was directed to children and their families aiming to increase awareness of those children. Results: Patients responded correctly to the questions, reported significant difference in their HRQOL at follow up r=0.68. also reported significant improvements on the General Health (P< .001) scales, the relationship between domains of HRQOL before &after the program was: physical health(r=0.36, p=0.01), psychological health (r=0.62, p<0.0001), social health (r=0.77, p<0.0001), environmental health (r=0.82, p<0.0001). HA1C at baseline&follow up were strongly correlated (r=0.54), HA1C increased significantly (mean 9.22 Vs 12.43, p<0.001). Conclusion: Health education programs are effective in increasing knowledge and awareness of children with type1 diabetes and their families and improving their quality of life.